Paracetamol-induced hepatic failure.
نویسندگان
چکیده
منابع مشابه
Acute lung injury in fulminant hepatic failure following paracetamol poisoning.
BACKGROUND There is little information on the incidence of acute lung injury or changes in the pulmonary circulation in acute liver failure. The aim of this study was to record the incidence of acute lung injury in fulminant hepatic failure caused by paracetamol poisoning, to document the associated pulmonary circulatory changes, and to assess the impact of lung injury on patient outcome. MET...
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OBJECTIVE To see whether intravenous acetylcysteine would improve outcome in patients with fulminant hepatic failure after paracetamol overdose. DESIGN A prospective randomised controlled study. SETTING The Institute of Liver Studies, King's College Hospital, London. PATIENTS 50 consecutive patients (21 male) aged 16-60 with fulminant hepatic failure after paracetamol overdose who had not...
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It has been postulated that deficiency of a putative natriuretic factor, or resistance to such a factor, may contribute to sodium retention in fulminant hepatic failure. Levels of plasma human atrial natriuretic factor (h-ANF), plasma renin activity, and aldosterone concentration were measured in 33 patients with fulminant hepatic failure due to paracetamol overdose, and 12 healthy control subj...
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OBJECTIVE To find out whether changes in the daily prothrombin time are of prognostic importance in patients with paracetamol induced fulminant hepatic failure. DESIGN Retrospective study. SETTING The Liver Unit, King's College Hospital, London. PATIENTS 150 Consecutive patients with paracetamol induced fulminant hepatic failure admitted between October 1986 and February 1989. MAIN OUTC...
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The relationship between serum transaminase levels and the extent of paracetamol-induced liver necrosis has been investigated in the rat. Three methods of histological quantitation were used to assess of necrosis--arbitrary grading, point counting, and the image-analysis computer. Highly significant correlations were obtained between the three methods and all were found to be reproducible. A cl...
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ژورنال
عنوان ژورنال: BMJ
سال: 1981
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.282.6275.1545-d